Analysis Service Overview

Overview

High Accuracy & Sensitivity Advanced instruments and algorithms ensure precise data across diverse samples

Customized Analytical Solutions Customized analysis for disease research, drug development, and precision medicine

Innovative Analysis Infrastructure AI-driven data processing accelerates turnaround time

Continuous Innovation Cutting-edge technologies and AI models are regularly updated to maintain competitiveness

Genomics

Genomics analysis enables comprehensive characterization of genomic variations and structural alterations across the genome, providing critical insights into the genetic basis of disease and molecular mechanisms

Leveraging advanced Next-Generation Sequencing (NGS) technologies and robust bioinformatics pipelines, genomics data supports disease-associated variant discovery, genetic risk assessment, and precision medicine strategies across research and clinical applications.

Available Services
  • Whole Genome, Whole Exome, and Targeted Sequencing
  • SNV, INDEL, CNV, and Structural Variant Detection
  • Variant Annotation and Pathogenicity Interpretation (ClinVar, gnomAD, etc.)
  • RNA-seq–based Gene Expression and Transcriptome Profiling
  • Functional Pathway and Gene Set Enrichment Analysis
Transcriptomics

Transcriptomics analysis investigates the transcriptome by profiling RNA expression in cells or tissues to understand gene expression changes and functional biological processes

RNA-seq based quantitative analysis combined with advanced bioinformatics enables the identification of disease mechanisms, biomarker discovery, and drug response analysis.

Available Services
  • Bulk RNA-seq Expression Profiling
  • Differential Gene Expression (DEG) Analysis
  • Alternative Splicing Analysis
  • Fusion Gene Detection
  • unctional Pathway and Gene Set Enrichment Analysis
  • Single Cell RNA-seq Analysis
Proteomics

Proteomics is a powerful analytical approach for comprehensively identifying and quantifying proteins, enabling a deep understanding of complex molecular mechanisms within biological systems.

Available Services
  • Qualitative and quantitative protein analysis
  • Post translational modifications analysis
  • Phosphoproteomics
  • DDA and DIA analysis
  • Targeted mass spectrometry (PRM, MRM)
Glycoproteomics

Glycoproteomics provides precise insights into protein glycosylation patterns and structural variations, offering essential information for understanding disease mechanisms, discovering biomarkers, and accelerating drug development.

Available Services
  • Qualitative and quantitative analysis of glycoproteins (N-glycosylation & O-glycosylation)
  • Site-specific Glycosylation Analysis
  • Identification of disease-associated glycosylation patterns
  • Characterization of therapeutic glycoproteins
  • Glycosylation consistency monitoring during biopharmaceutical production
Metabolomics

Metabolomics is a powerful tool for profiling metabolic changes to understand biological processes and discover disease-related biomarkers

Using high-resolution mass spectrometry, we provide both untargeted and targeted analysis, offering key insights for diagnosis, drug response, and precision medicine.

Available Services
  • Qualitative and quantitative metabolite profiling
  • DDA and DIA analysis
  • Metabolic pathways analysis
  • Targeted mass spectrometry (PRM, MRM)
Olink Proteomics

Olink analysis is a high-sensitivity and high-specificity analytical service that quantifies multiple protein biomarkers from small sample volumes using Proximity Extension Assay (PEA) technology.

When two antibodies bind to the same target protein, their DNA reporters form a detectable sequence, which is then quantified by qPCR or NGS. This technology is widely used for biomarker discovery and validation in research areas including oncology, immunology, cardiovascular disease, and neurological disorders.

Available Services
  • Large-scale protein profiling using Olink Explore HT
  • Olink Target 96/48 disease-focused panel analysis
  • Multiplex protein analysis using small volumes of plasma or serum
  • NPX-based relative quantification and QC reporting
  • Multi-omics integration analysis and biomarker candidate identification
Bioinformatics Analysis

Bioinformatics enables breakthroughs in life science research by extracting meaningful insights from complex biological data across genomics, proteomics, metabolomics, and beyond.

At CellKey AI, we leverage advanced algorithms and cloud-based infrastructure to deliver comprehensive biological insights and data-driven discoveries.

Available Services
Genomics
  • DNA/RNA variant analysis (SNVs, InDels, etc.)
  • Interpretation of gene panel, whole-genome, and whole-exome sequencing data
  • Variant annotation and functional impact analysis
  • Discovery of disease-associated genes and biomarkers
Transcriptomics
  • Quantitative gene expression analysis based on RNA-seq
  • Differentially expressed gene (DEG) analysis
  • Functional enrichment and pathway analysis
  • Gene network analysis and biomarker discovery
Proteomics
  • Quantitative protein expression analysis (Label-free, SILAC, TMT)
  • Protein–protein interaction (PPI) network analysis
  • Biomarker discovery
Metabolomics
  • Metabolite profiling and quantification
  • Metabolic network analysis
Multiomics Integration
  • Integrated analysis of genomics, proteomics, and metabolomics
  • Pathway analysis and network modeling
  • AI/ML-based biomarker discovery
Biopharmaceutical Characterization

With advanced analytical technologies and expertise, we precisely characterize the physicochemical and biological properties of biopharmaceuticals to ensure quality and safety.

Category Item Analysis Purpose
Identification of antibody
  • Intact Mass
  • Peptide mapping fingerprinting
  • Full length sequencing
  • N/C terminal determination
  • Amino acid composition
  • Extinction Coefficient
  • Confirmation of the total molecular weight of antibodies and ADCs
  • Verification of protein amino acid sequences and modifications
  • Complete sequence confirmation of antibodies
  • Determination of N-terminal and C-terminal sequences of proteins
  • Analysis of amino acid composition of proteins
  • Measurement of optical absorbance coefficients of proteins
Modification analysis
  • Modification (Oxidation, deamidation)
  • IsoAsp analysis
  • Glycation analysis
  • PEGylation analysis
  • Succinimeide analysis
  • Disulfide bond analysis
  • Free thiol analysis
  • Identification of chemical modifications such as oxidation and deamidation
  • Detection of IsoAsp formation
  • Identification of glycation sites
  • Confirmation of PEG (polyethylene glycol) conjugation
  • Detection of succinimide intermediates
  • Determination of disulfide bond locations and status
  • Verification of the presence of free thiol groups
Glycan analysis
  • Monosaccharide composition
  • Sialic acid compositon
  • N-linked glycan profile
  • O-linked glycan profile
  • N-Glycosylation site
  • O-Glycosylation site
  • Analysis of monosaccharide composition
  • Composition and content analysis of sialic acids
  • Analysis of N-linked glycan structures
  • Analysis of O-linked glycan structures
  • N-glycosylation site analysis
  • O-glycosylation site analysis
Structure analysis
  • UV
  • Flurescence
  • CD
  • DSC
  • FT-IR
  • Ultraviolet absorbance analysis
  • Fluorescence characteristic analysis
  • Secondary structure analysis of proteins
  • Thermal stability analysis of proteins
  • Structural analysis of proteins
Aggregation analysis
  • DLS
  • SEC-UPLC
  • Analysis of particle size and distribution
  • Determination of protein molecular weight distribution
Antibody-Drug Conjugate (ADC)

The complex nature of antibody-drug conjugates (ADCs) makes analytical biochemistry essential for their discovery and development. At Sterling, our specialized ADC facility provides tailored analytical and quality control services

With expertise in biopharmaceuticals, our team conducts detailed analyses to ensure a thorough understanding of ADC potency and characteristics, supporting the development of high-quality therapeutics.

Available Services
  • Total antibody analysis
  • Antibody-conjugated drug analysis
  • Free payload analysis
  • Linker stability analysis
  • DAR(Drug-to-Antibody Ratio) analysis
Specialized Analysis

In addition to standard multi-omics services, customized analytical solutions are available for specific research and development needs

Participating service providers support complex projects including integrated multi-omics studies, biopharmaceutical characterization, and custom analytical method development. These services are typically offered through consultation to design optimized analytical strategies for each project.

Available Services
  • Integrated multi-omics analysis (genomics, transcriptomics, proteomics, metabolomics)
  • AI-driven biomarker discovery and pathway analysis
  • Cross-omics data integration and systems biology analysis
  • Study design consultation for complex biological projects
  • LC–MS/MS method development for small molecules
  • Quantitative bioanalysis method development
  • Analytical method validation

Our services span analysis of diverse sample types,
encompassing method development and validation for novel compounds.

Biological Samples
  • Serum, Plasma, Cell line, Tissue, CSF etc.
  • Glycoprotein
  • Exosome, Cell lysate, Secretome
Biopharmaceuticalproducts
  • Antibody, Fusion protein, ADC
Food, Cosmetics, and Other Industries
  • Protein/Glycoprotein raw material
  • Development and validation of analytical methods for other target compounds
Sample Requirements
  • Protein Quantity: >100 μg
  • Cell count: >10⁷
  • EV particles: >10¹⁰